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Cyclin C was cloned as a growth-promoting G1 cyclin, and was also shown to regulate gene transcription. Here we report that in vivo cyclin C acts as a haploinsufficient tumour suppressor, by controlling Notch1 oncogene levels. Cyclin C activates an 'orphan' CDK19 kinase, as well as CDK8 and CDK3. Our Products >> RS Products AKR Picatinny Rail Mount The AKR is the latest AK-300 system compatible optics mount from Royally Screwed! It offers a super-low profile with 12-slot M1913 picatinny rail that is perfect for mounting everything from fixed base optics and EOTechs to full-out rifle scopes! TANJUG